top of page
This site was designed with the
.com
website builder. Create your website today.Start Now

  1. Tsirigotaki A, Chatzi KE, Koukaki M, De Geyter J, Portaliou AG, Orfanoudaki G, Sardis MF, Trelle MB, Jørgensen TJD, Karamanou S, Economou A., Long-Lived Folding Intermediates Predominate the Targeting-Competent Secretome. Structure. 2018 Mar 28. 

  2. Sardis, M.F.*, Tsirigotaki A.*, Chatzi, K.E., Portaliou, G. A., Gouridis, G., Karamanou, S. and Economou, A. (2017) Preprotein conformational dynamics drive bivalent translocase docking and secretion. (*Equal contribution) Structure. 2017 Jul 5;25(7):1056-1067. (doi: 10.1016/j.str.2017.05.012.)

  3. Katerina E. Chatzi*, Marios Frantzeskos Sardis*, Alexandra Tsirigotaki, Marina Koukaki, Nikolina Šoštarić, Albert Konijnenberg, Frank Sobott, Charalampos G. Kalodimos, Spyridoula Karamanou and Anastassios Economou, Translocase targeting signals in mature domains are essential for preprotein secretion. (*Equal contribution)  J Cell Biol. 2017 May 1;216(5):1357-1369. (doi: 10.1083/jcb.201609022.)                             [In focus comment by B.Short doi: 10.1083/jcb.201704081]

  4. Papanastasiou M., Orfanoudaki G., Kountourakis N., Koukaki M., Sardis M.F., Aivaliotis M., Tsolis K.C., Karamanou S., Economou A., Rapid label-free quantitative analysis of the E. coli BL21(DE3) inner membrane proteome. Proteomics. 2016 Jan;16(1):85-97. (doi: 10.1002/pmic.201500304.)

  5. De Waelheyns E., Segers K., Sardis M.F., Anné J., Nicolaes G.A., Economou A., Identification of small-molecule inhibitors against SecA by structure-based virtual ligand screening. J. Antibiot. 2015 Nov;68(11):666-73. (doi: 10.1038/ja.2015.53.)

  6. Chatzi K.E., Sardis M.F., Economou A., Karamanou S., SecA-mediated targeting and translocation of secretory proteins. Biochim. Biophys. Acta, 2014 Aug;1843(8):1466-74. (doi: 10.1016/j.bbamcr.2014.02.014. )

  7. Gouridis, G., Karamanou S., Sardis M.F., Schärer M., Capitani G. and Economou A., Quaternary dynamics of the SecA motor drive translocase catalysis. Mol. Cell., 2013 Dec 12;52(5):655-66). (doi: 10.1016/j.molcel.2013.10.036.)

  8. Papanastasiou M, Orfanoudaki G., Koukaki M., Kountourakis N., Sardis M.F., Aivaliotis M., Karamanou S., Economou A., The Escherichia coli peripheral inner membrane proteome. Mol. Cell. Proteomics, 2013 Mar;12(3):599-610. (doi: 10.1074/mcp.M112.024711.)

  9. Chatzi K.E., Sardis M.F., Karamanou S. and Economou A., Breaking on through to the other side: protein export through the bacterial Sec system. Biochem. J., 2013 Jan 1;449(1):25-37. (doi: 10.1042/BJ20121227.)

  10. Kapellios E.A., Karamanou S., Sardis M.F., Aivaliotis M., Economou A. and Pergantis S.A., Using Nanoelectrospray Ion Mobility Spectrometry (GEMMA) to Determine the Size and Relative Molecular Mass of Proteins and Protein Assemblies: A Comparison with MALLS and QELS. Anal. Bioanal. Chem., 2011 Mar;399(7):2421-33. (doi: 10.1007/s00216-010-4634-3.)

  11. Sardis M.F., and Economou, A., SecA: a tale of two protomers. Mol. Microbiol., 2010 Jun 1;76(5) 1070-81. (doi: 10.1111/j.1365-2958.2010.07176.x)

  12. Marios-Frankiskos Sardis, Panagiota M., Katerina B., Athanassakis I., Serum-derived MHC class II molecules: potent regulators of the cellular and humoral immune response. Immunobiology, 2010 Mar;215(3):194-205. (doi: 10.1016/j.imbio.2009.04.005.)

Peer-reviewed Publications

- Thomas A. Edison-

“I have not failed. I've just found 10,000 ways that won't work.”

PUBLICATIONS

  1. Marios F. Sardis, Stephan Zimmermann, Victoria Feher, Jesper Sørensen, Chris Smith, Laurence Hall, Mike Greaney, Rommie E. Amaro, Achim Schnaufer. Kinetoplast RNA editing as a drug target for trypanosomatid diseases. Edinburgh Infectious Diseases symposium, Edinburgh, Scotland, U.K., 2016 (Poster presentation). â€‹

  2. Marios F. Sardis, Stephan Zimmermann, Victoria Feher, Jesper Sørensen, Chris Smith, Laurence Hall, Mike Greaney, Rommie E. Amaro, Achim Schnaufer. Kinetoplast RNA editing as a drug target for trypanosomatid diseases. COST Action CM1307 Working Groups 1 and 4 Meeting, Targeting metabolism and transport in parasites: drugs and delivery systems Porto, Portugal 2016.  (Oral Presentation).

  3. Karamanou, S., Chatzi, K., Sardis, M.F., Tsirigotaki, A., Orfanoudaki, G., de Geyter, J., Portaliou, A., Tsolis, K., Loos, M., Papanastasiou, M., Trelle, M.B., Saio, T., Jørgenson, T.J., Kalodimos, C.G. and Economou A.,Deciphering bacterial protein secretion using a multi-pronged approach: from proteins to proteomics. 4th Symposium on Structural Proteomics 2014, Antwerp, Belgium 2014, (Poster presentation). 

  4. Karamanou, S., Chatzi, K., Sardis, M.F., Tsirigotaki, A., Orfanoudaki, G., de Geyter, J., Portaliou, A., Tsolis, K., Loos, M., Papanastasiou, M., Trelle, M.B., Saio, T., Jørgenson, T.J., Kalodimos, C.G. and Economou A.,Protein secretion: from function to structure to biophysics to proteomics and back, BePAc 2014 - From analytical to functional proteomics, Brussels, Belgium 2014, (Poster presentation). 

  5. Chatzi K., Sardis M.F., Orfanoudaki G., Koukaki M., Karamanou S., Economou A., Mature domain targeting signals, EMBO conference, “Molecular Machines: Lessons from Integrating Structure, Biophysics and Chemistry”, Heidelberg, 2013, (Poster presentation).

  6. Chatzi K., Sardis M.F., Orfanoudaki G., Koukaki M., Karamanou S., Economou A., Mature domain targeting signals, EMBO conference, “The biology of molecular chaperones: from organelles and cells to misfolding diseases”, “Sardinia, 2013, (Poster presentation).

  7. Chatzi K., Sardis M.F., Orfanoudaki G., Koukaki M., Karamanou S., Economou A., Mature domain targeting signals, EMBO conference on protein transport, Dubrovnik, 2013, (Poster presentation).

  8. Papanastasiou M, Orfanoudaki G., Koukaki M., Kountourakis N., Sardis M.F., Aivaliotis M., Karamanou S. Economou A., The Escherichia coli Inner Membrane Proteome, 63th Pan-Hellenic Congress in Biochemistry and Molecular Biology, IMBB FORTH, Crete, Greece, 2012, (Poster presentation).

  9. Chatzi K., Orfanoudaki G., Sardis M.F., Koukaki M., Karamanou S., Economou A., Leaving the cytoplasm: Secretory protein targeting signals, 63th Pan-Hellenic Congress in Biochemistry and Molecular Biology, IMBB FORTH, Crete, Greece 2012, (Poster presentation).

  10. Sardis M.F., Chatzi K., Koukaki M., Karamanou S., Economou A.,Promiscuous preprotein recognition by SecA , 63th Pan-Hellenic Congress in Biochemistry and Molecular Biology, IMBB FORTH, Crete, Greece 2012, (Poster presentation).

  11. Sardis M.F., Chatzi K., Koukaki M., Karamanou S., Economou A., Promiscuous preprotein recognition by SecA, Sofia School of Protein Science: Structure and Dynamics of Biological Macromolecules Institute of Molecular Biology Roumen Tsanev, Sofia, Bulgaria, 2012, (Poster/Best poster presentation, Oral presentation). 

  12. Sardis M.F., Gouridis G., Koukaki M., Chatzi K., Karamanou S., Economou A., Long-range interaction between the preprotein binding domain and the motor of SecA, Protein Transport Systems, Structure mechanism and medical aspects, EMBO conference series, Sardinia, Italy, 2011, (Poster presentation).

  13. Sardis M.F., Gouridis G., Koukaki M., Chatzi K., Karamanou S., Economou A., Long-range interaction between the preprotein binding domain and the motor of SecA, 1st International Proteomics Conference in Crete – IPCC-01, 2010, (Poster presentation).

  14. Kapellios E., Karamanou S., Sardis M.F., Aivaliotis M., Economou A., Pergantis S.A., Using Nanoelectrospray Ion Mobility Spectrometry (GEMMA) to Determine the Size and Relative Molecular Mass of Proteins and Protein Assemblies: A comparison with MALLS and QELS, 1st International Proteomics Conference in Crete – IPCC-01, 2010, (Poster presentation).

  15. Papanastasiou M., Sardis M.F., Orfanoudaki G., Giapitzaki G., Aivaliotis M., Kountourakis N., Karamanou S., Economou A., Comprehensive characterization of the Escherichia coli cell envelope using a nanoLC-LTQ orbritrap MS, 1st International Proteomics Conference in Crete – IPCC-01, 2010, (Poster, Oral presentation).

  16. Sardis M.F., Gouridis G., Koukaki M., Karamanou S., Economou A., Long-range interaction between the preprotein binding domain and the motor of SecA, FEBS Advanced Lecture Course Analysis and Engineering of Biomolecular Systems, Spetses Greece, 2010, (Poster presentation).

  17. Papanastasiou M., Sardis M.F., Aivaliotis M., Karamanou S., Economou A., Comprehensive Characterization of the Inner Membrane Proteome of Escherichia coli Using a nanoLC-LTQ Orbitrap MS, 58th ASMS Conference on Mass Spectrometry conference, 2010, (Poster presentation).

  18. Kapellios E.A., Karamanou S., Sardis M.F., Aivaliotis M., Pergantis S.P. and Economou A., Nanoelectrospray Differential Ion Mobility Spectrometry for Protein Sizing and Molecular Mass Determination: Method Development and Validation, 18th International Mass Spectrometry Conference, 2009, (Poster presentation).

  19. Sardis M.F., Gouridis G., Koukaki M., Karamanou S., Economou A., PBD swiveling is essential for translocase catalysis, PBD swivelling is essential for translocase catalysis, Summer school on Protein Biotechnology organized by the Protein Biotechnology Graduate Program, Department of Biology, University of Crete, held at Fodele, in Crete, 2009, (Poster, Oral presentation).

  20. Sardis M.F., Gouridis G., Koukaki M., Karamanou S., Economou A., PBD swivelling is essential for translocase catalysis, Summer school on Protein Biotechnology organized by the Protein Biotechnology Graduate Program, Department of Biology, University of Crete, held at Fodele, in Crete, 2008, (Poster, Oral presentation).

  21. Sardis M.F., Gouridis G., Koukaki M., Karamanou S., Economou A., Functional Characterization of the Preprotein Binding Domain of SecA, 59th Pan-Hellenic Congress in Biochemistry and Molecular Biology, Athens, Greece, 2007, (Poster presentation).

  22. Sardis M.F., Athanassakis I., Modulation of spleen cell responses by soluble MHC molecules, 1st Joint Meeting of European National Societies of Immunology, 16th European Congress of Immunology, 2006, (Poster presentation).

Conference Presentations
bottom of page